The author of ASP.NET 3.5 Website Programming: Problem - Design - Solution came to our town to talk about the lessons learned from developing with the Entity Framework with the Beer House project. It was great, and I had to purchase the book when it became available! He walks you through developing a real-life application in ASP.NET 3.5 using the Entity Framework; no impractical examples here.
Many developers dive into writing an application without giving consideration to the overall architectural concerns that are necessary for a well-designed web application. Chris Love walks you through these concerns from the multiple application tiers to logging, instrumentation, and finally deployment.
I am currently a fan of ASP.NET MVC, but if you're still programming Web Forms, and many are, this is the book for you.